School of Pharmacy, Institute for Drug Research
Brief Summary of research:
Polymeric Nanocarriers for Drug Targeting and Improved Drug Delivery.
Specific research topics related to Nanoscience and Nanotechnology:
- Enhanced percutaneous permeation of poorly permeating drugs by means of lipid and polymeric nanocarriers
- Targeted delivery of chemotherapeutic drugs to specific cancerous cells using nanoparticles conjugated to monoclonal antibodies for decreased toxicity, enhanced drug-cell penetration and performance.
- Various formulations of natural and synthetic cannabinoids are being investigated in original self-nanoemulsifying formulations , nanoparticles , nanocapsules , some of them embedded in Microparticles for improved oral bioavailability of these poorly absorbed compounds.
- Oxaliplatin palmitate acetate, a novel Pt(IV) chemical entity, derived from Oxaliplatin is more lipophilic than OXA and exhibits a quick clearance rate from the blood circulation. Its systemic prolonged exposure needs to be investigated using nano-delivery systems to reach better efficacy and safety profile .
Design of Nanoemulsions and Nanoparticles for improved ocular drug delivery.