Brief Summary of research:
Our group is interested in the structural and synaptic changes induced by depression and antidepressants. We focus on Neurensin-2, a recently identified depression-mediating protein that is also regulated by antidepressants.
Specific research topics related to Nanoscience and Nanotechnology:
The expression of Neurensin-2 remarkedly regulates the neuronal function and emotional behavior, possibly by synapse morphology alterations.
By applying electron microscopy imaging approaches, we aim to elucidate dynamic changes in the neuronal nanostructure after stress, treatment with antidepressants, and altered Neurensin-2 expression.