Brief Summary of research:
This laboratory is dedicated to the direct measurement of these characteristics of protein systems one molecule at a time, protein-after-protein. Using these techniques we study the molecular mechanisms leading to bacterial resistance to antibiotic molecules, through structural changes in the bacterial transcription complex. Additionally, we study the mechanisms allowing the transduction of chemical signals through proteins mechanically, and how they assist in transcriptional regulation in bacteria and in signal transduction in the eukaryotic cell.
Specific research topics related to Nanoscience and Nanotechnology:
Fabrication of micro & nano fluidic chips.