Dr. Haitham Amal

Haitham Amal
Dr.
Haitham
Amal
School of Pharmacy - Institute for Drug Research
+972-2-6758683
haitham.amal@mail.huji.ac.il

Brief Summary of research: 

In the field of omics technology, my group use nano-LC system combined with mass spec to identify posttranslational modifications (PTMs) such as S-nitrosylation and phosphorylation in order to provide critical information on the cellular state and cell signaling. The ultimate goal is to develop nano-based drug delivery systems to treat autism spectrum disorder, Alzheimer's disease, and other neurological disorders. The Amal combines biochemical, omics, bioinformatics, pharmacological, and behavioral tools to reach their ultimate goals
Throughout my Ph.D. studies, we developed novel technology-based nano-sensors for building algorithms for disease diagnosis via exhaled breath. We designed analyzer devices from fabricated nanomaterial-based sensor arrays that were evaluated in 14 hospitals worldwide and developed analytical chemistry techniques for the detection of biomarkers for 17 different diseases

Specific research topics related to Nanoscience and Nanotechnology:

Throughout my scientific career and together with other scientists, we developed novel technology-based nano-sensors for building algorithms for disease diagnosis via exhaled breath. We designed analyzer devices from fabricated nanomaterial-based sensor arrays that were evaluated in 14 hospitals worldwide and developed analytical chemistry techniques for the detection of biomarkers for 17 different diseases. I published 12 papers in this field

In the field of proteomics, my group use nano-LC system combined with mass spec to identify posttranslational modifications (PTMs) such as S-nitrosylation and phosphorylation in order to provide critical information on the cellular state and cell signaling. Our approach will lead to the discovery of drug targets. The ultimate goal is to develop nano-based drug delivery to treat autism spectrum disorder, Alzheimer's disease, and other neurological disorders. I published 8 papers in this field